Professor Robin Franklin

The Franklin Lab is interested in the mechanisms of CNS regeneration with a particular focus on remyelination, an adult stem/precursor cell-mediated process in which new myelin sheaths are restored to demyelinated axons. Using developmental-, transplantation-, chemical-, transgenic- and viral vector-based in vivo models in both mammals and fish, combined with tissue culture studies, we are examining extrinsic (environmental) and intrinsic (transcriptional) factors that govern the differentiation of adult neural stem/precursor cells into oligodendrocytes and other glia following CNS injury. We also work on the stem/precursor cells of the adult olfactory epithelium. Professor Franklin is also Director of the MS Society Cambridge Centre for Myelin Repair.